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Glossary 5-FU 5-fluorouracil ATG Autophagy-related protein CD44 kd CD44 knockdown CD44v2 CD44 variant exon v2 CD44v3 CD44 variant exon v3 CD44v5 CD44 variant exon v5 CD44v6 CD44 variant exon v6 CD44v7 CD44 variant exon v7 CD44v9 CD44 variant exon v9 c-Met Mesenchymal epithelial transition factor receptor CQ Chloroquine DSS Disease-specific survival DUB Deubiquitinating enzyme ECD Extracellular domain EGF Endothelial growth factor ERBB2 Receptor tyrosine-protein kinases 2 FOLFOX Folinic acid, 5-FU and oxaliplatin GSH Reduced glutathione HA Hyaluronan HABD HA-binding domain HGF Hepatocyte growth factor HMW High molecular weight HS Heparan sulfate ICD Intracellular domain IHC Immunohistochemistry ITG Integrin LC3 Microtubule-associated protein 1A/1B-light chain 3 Mer/NF2 Merlin/neurofibromin-2 MMPs Metalloproteinases MST1/2 Mammalian STE20-like kinase 1 and 2 mTOR Mammalian target of rapamycin MUC1 Mucin 1 MUC1-C Mucin 1 C-terminal subunit NCCD Nomenclature Committee on Cell Death NLS Nuclear localization signal NSCLC Non-small cell lung cancer NSE Neuron-specific enolase OPN Osteopontin OS Overall survival OTUB1 Ubiquitin thioesterase/otubain-1 PAAD pancreatic cancer PAR1b Polarity-regulating serine/threonine kinase PCD Programmed cell death PHF8 PHD finger protein 8 PRAD prostate cancer PSA Prostate antigen QC Quinacrine RA Rheumatoid arthritis RFS Recurrence-free survival RNA-seq RNA sequencing ROS Reactive oxygen species RTKs Receptor tyrosine kinases SAS Sulfasalazine SMCs Smooth muscle cells TCGA The Cancer Genome Atlas TG2 Transglutaminase 2 TMD Transmembrane domain TURBT Transurethral resection of bladder tumor VEGFR-2 Vascular endothelial growth factor receptor 2 YAP Yes-associated protein References 1 AaltomaaS.LipponenP.Ala-OpasM.KosmaV.-M

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RLS and PLMD: Science, Solutions, and Genetics Restless leg syndrome (RLS) is characterized by a feeling that you have to move your legs, usually at night when you are in bed