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Figure 1 2 Mechanisms and consequences of diabetes-induced gut microbiota dysbiosis 2.1 Mechanisms underlying gut dysbiosis-induced diabetes Although the gut microbiota is initially established at birth, it evolves dynamically throughout life, modulated by host age, dietary patterns, and physical activity (Rinninella et al., 2019)

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To further synthesize the complex and multidimensional interactions between the gut microbiome and transplant outcomes, several conceptual and mechanistic models have been proposed