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The binding of AGEs to their receptor (RAGE) activates the AGEs/RAGE signaling pathway, inducing inflammation, oxidative stress, cell apoptosis, insulin resistance, and damage to pancreatic β cells 92
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[DOI] [PMC free article] [PubMed] [Google Scholar] 6.Junqueira VB, Barros SB, Chan SS, Rodrigues L, Giavarotti L, Abud RL, Deucher GP
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