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Most require refrigeration and have a 28-day in-use expiration after first puncture Travel tips: Use an insulated medication travel case with ice packs for trips Never place semaglutide in checked luggage (temperature-controlled cargo holds can freeze) Carry it in your carry-on bag with a note from your prescriber if flying TSA allows injectable medications through security - keep them in their original packaging or bring your prescription label If staying somewhere without refrigeration, brand-name pens can be kept at room temperature (under 86 degrees F) for up to 56 days Hotel rooms: don't leave on the windowsill, near a heater, or in a car - heat above 86 degrees F can degrade the medication Semaglutide Side Effects - Complete Guide Every medication has side effects, and semaglutide is no exception

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Most patients report noticeable improvements in energy and mood within weeks