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Efficacy of hypochlorous acid scavengers in the prevention of protein carbonyl formation

Aishi

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Several studies using animal models and the strategy of GSH depletion by buthionine sulfoximine as an inhibitor of γ -GCS demonstrated an increase in oxidative stress markers in the liver and various other organs in vivo [22], and the treatment of cells with GSH or N-acetylcysteine limits such damage and renders cells or tissues less susceptible to oxidative stress [23]