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Importantly, it should be highlighted that when CD38 is catalyzing the degradation of NAD to ADPR, or the cyclization of NAD to cADPR, there is NAD consumption and nicotinamide generation, leading to the crucial role of CD38 in tissue NAD and nicotinamide homeostasis [6, 34-35, 38-40]
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Oxidative stress induces imbalance of adipogenic/osteoblastic lineage commitment in mesenchymal stem cells through decreasing SIRT1 functions
Exocrine pancreatic insufficiency (EPI) prevents animals from being able digest and absorb the nutrients from food
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