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Dityrosine cross-linking refers to the formation of covalent bonds between two tyrosine residues on the same or different proteins, catalyzed by oxidative conditions, particularly through the action of peroxidases or ONOO − [106,107]

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Its conclusion was that preclinical evidence supports BPC-157’s potential in musculoskeletal healing but that human clinical data remains “extremely limited.” The review notes that BPC-157 is “increasingly used by clinicians and athletes” despite the absence of FDA approval and the WADA ban