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An increase in levels of total protein carbonyls, TBARS and advanced glycation end products (AGEs) were observed in the cortex of DS foetal brains compared with controls (Odetti et al., 1998), while a marked accumulation of nitro tyrosine, 8-hydroxy-2-deoxyguanosine, and oxidized proteins was reported in the cerebral neuron cytoplasm in DS (Nunomura et al., 2000)
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US$40
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