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530 vi) heterologous expression of the phomactin diterpenoids was shown to require only two enzymes: a cyptic terpene cyclase to convert GGPP into phomactatriene (see Figure 10), and a P450 monooxygenase to catalyze oxidation at multiple sites along the phomactatriene scaffold to yield phomactin B4 ( 40 )
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