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osmotic and oxidative stresses are associated with proteostasis disruption), and WT or modest suppression ( ifd-2(Δ) ) of baseline gst-4 ::GFP expression (GST-4::GFP is a daf-16 /FOXO/ SKN-1/NRF responsive glutathione-S-transferase reporter commonly used to report stress conditions 39 ) (Supplementary Fig
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Owing to the localized mechanism of action and the general absence of systemic adverse effects, TFFields represent a strategy that should be explored for novel combination therapies in addition to the standard of care [51]
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