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Klotho Deficiency Causes Heart Aging via Impairing the Nrf2-GR Pathway | Circulation Research
In fibroblasts it triggers the FAK-paxillin pathway, which increases cell migration and survival, and it upregulates the expression of early growth response genes (egr-1 and its co-repressor NAB2), which regulate cytokine and growth-factor production during wound healing
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