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Allergic reactions (e.g., ocular swelling, eyelid edema, and conjunctival hyperemia), corneal edema, iritis, ocular inflammation, ocular irritation, superficial keratitis, and superficial ocular infection have been reported in 1% to 10% of patients

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92 Memantine was the most recent FDA-approved therapy for moderate to severe AD, where approval was granted in 2003, and it continues to be the only medication in its category