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Moreover, gspD cells grown under conditions similar to the gliding motility assay, but plated on soft agar to promote S-motility, demonstrated swarm expansion typical of S-motility in both the absence and presence of copper (Fig
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In vitro studies have demonstrated that overexpression of Angiogenin, a RNase associated with familial ALS, activates NRF2 which protects astrocytes from oxidative stress (Hoang et al., 2019) and curcumin mediated NRF2 induction ameliorates mitochondrial dysfunction (Lu et al., 2012)
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