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Adult participants, aged between 18 and 70 years, exhibiting HAMD scores ranging from 21 to 31, were allocated to receive either a low-dose of SHR-5 (340 mg/day), a high-dose of SHR-5 (680 mg/day), or a placebo (60)
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Although d-penicillamine also shared advantage of oral administration when prescribed at 250 mg given four times for five days of therapy or 40 mg/kg/day for chronic therapy
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